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suppressor mutation : ウィキペディア英語版
suppressor mutation
A suppressor mutation is a second mutation that alleviates or reverts the phenotypic effects of an already existing mutation. Genetic suppression therefore restores the phenotype seen prior to the original background mutation.〔Hartwell, L. H., Hood, L., Goldberg, M. L., Reynolds, A. E., Silver, L. M., & Veres, R. C. (2008). Genetics: From Genes to Genomes. New York: McGraw-Hill.〕 Suppressor mutations are useful for identifying new genetic sites which affect a biological process of interest. They also provide evidence between functionally interacting molecules and intersecting biological pathways.〔Hodgkin J. Genetic suppression. 2005 Dec 27. In: WormBook: The Online Review of C. elegans Biology (). Pasadena (CA): WormBook; 2005-.〕
==Intragenic vs. Intergenic Suppression==


抄文引用元・出典: フリー百科事典『 ウィキペディア(Wikipedia)
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